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Article

Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity.

PLoS neglected tropical diseases - 1 Sept 2020

Murphy Anna, Cwiklinski Krystyna, Lalor Richard, O'Connell Barry, Robinson Mark W, Gerlach Jared, Joshi Lokesh, Kilcoyne Michelle, Dalton John P, O'Neill Sandra M

Abstract excerpt

Parasite-released extracellular vesicles (EVs) deliver signals to the host immune system that are critical to maintaining the long-term relationship between parasite and host. In the present study, total EVs (FhEVs) released in vitro by adults of the helminth parasite Fasciola hepatica were isolated using a recently described gravity flow method that protects their structural integrity. The FhEVs molecular cargo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32898175
DOI: 10.1371/journal.pntd.0008626
PMCID: PMC7521716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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