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The interaction between cellular senescence and chronic kidney disease as a therapeutic opportunity

26 Aug 2022

Abstract excerpt

Chronic kidney disease (CKD) is an increasingly serious public health problem in the world, but the effective therapeutic approach is quite limited at present. Cellular senescence is characterized by the irreversible cell cycle arrest, senescence-associated secretory phenotype (SASP) and senescent cell anti-apoptotic pathways (SCAPs). Renal senescence shares many similarities with CKD, including etiology,...

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PMID: 36091755
DOI: 10.3389/fphar.2022.974361

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