Article
An integrated organoid omics map extends modeling potential of kidney disease
2022-10-05
Abstract excerpt
<title>Abstract</title> <p>Kidney organoids are a promising model to study kidney disease, but use is constrained by limited knowledge of their functional protein expression profile. We aimed to define the organoid proteome and transcriptome trajectories over culture duration and upon exposure to TNFα, a cytokine stressor. Older organoids increased deposition of extracellular matrix but decreased expression of gl...
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Identifiers and source
- Literature Corpus work
- 797cf39c-4283-5bc7-9fb0-e655c1cf675f
- DOI
- 10.21203/rs.3.rs-2109564/v1