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Article

Hyposialylation Must Be Considered to Develop Future Therapies in Autoimmune Diseases

26 Mar 2021

Abstract excerpt

Autoimmune disease development depends on multiple factors, including genetic and environmental. Abnormalities such as sialylation levels and/or quality have been recently highlighted. The adjunction of sialic acid at the terminal end of glycoproteins and glycolipids is essential for distinguishing between self and non-self-antigens and the control of pro- or anti-inflammatory immune reactions. In autoimmunity,...

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PMID: 33810246
DOI: 10.3390/ijms22073402

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