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Characteristics of Subtypes Within Microsatellite Instability-high Gastric Cancer Based on a Gene Signature Related to Immune Microenvironment Components

2020-06-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Gastric cancer patients with microsatellite instability-high (MSI-H) status have a better clinical prognosis and higher response rate to immune checkpoint inhibitors. However, recent studies have suggested that some molecular pathways in MSI-H tumors could affect tumor immune microenvironment (TIME) components, thereby leading to immunotherapy resistance. We aim...

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Literature Corpus work
79687c5e-bed5-5d7c-a7d7-f00fa6d190bf
DOI
10.21203/rs.3.rs-31506/v1
Open publication

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