Article
Immunogenomic characterization in gastric cancer identifies microenvironmental and immunotherapeutically relevant gene signatures.
Immunity, inflammation and disease - 1 Jan 2022
Han Xiao, Lu Heyue, Tang Xiaojun, Zhao Yao, Liu Hongxue
Abstract excerpt
BACKGROUND: Multiple molecular subtypes with distinct clinical outcomes in gastric cancer have been identified. Nonetheless, the immunogenomic subtypes of gastric cancer and its mediated tumor microenvironment (TME) characterizations have not been fully understood. METHODS: Six gastric cancer cohorts with 1506 samples were obtained. Unsupervised methods were used to perform immunogenomic phenotype clustering. The...
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