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Somatic mutational profiles of stage II and III gastric cancer according to tumor microenvironment immune type

21 Sept 2018

Abstract excerpt

Abstract We aimed to determine somatic mutational profiles of stage II/III gastric cancers (GCs) according to their tumor microenvironment immune types (TMITs), which classify cancer based on co‐assessment of PD‐L1 expression and CD8 + tumor infiltrating lymphocytes. Eighty patients with stage II/III GC were classified as follows: TMIT I (PD‐L1 + /CD8 High ), TMIT II (PD‐L1 − /CD8 Low ), TMIT III (PD‐L1 + /CD8...

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PMID: 30239046
DOI: 10.1002/gcc.22683

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