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Article

Heterogeneity of MSI-H gastric cancer identifies a subtype with worse survival

13 Mar 2020

Abstract excerpt

BACKGROUND: Microsatellite instability-high (MSI-H) tumour patients generally have a better prognosis than microsatellite-stable (MSS) ones due to the large number of non-synonymous mutations. However, an increasing number of studies have revealed that less than half of MSI-H patients gain survival benefits or symptom alleviation from immune checkpoint-blockade treatment. Thus, an in-depth inspection of...

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PMID: 32170001
DOI: 10.1136/jmedgenet-2019-106609

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