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Four distinct immune microenvironment subtypes in gastric adenocarcinoma with special reference to microsatellite instability

1 Jan 2018

Abstract excerpt

Introduction Programmed death-ligand 1 (PD-L1) can be overexpressed in tumours other than Epstein-Barr virus (EBV)-positive (EBV + ) or microsatellite instability-high (MSI-H) gastric cancer (GC) subtypes. We aimed to determine the tumour immune microenvironment (TME) classification of GC to better understand tumour–immune interactions and help patient selection for future immunotherapy with special reference to...

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PMID: 29636988
DOI: 10.1136/esmoopen-2018-000326

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