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Five EMT‐related genes signature predicts overall survival and immune environment in microsatellite instability‐high gastric cancer

4 Jul 2022

Abstract excerpt

Abstract Background Microsatellite instability‐high (MSI‐H) subgroup of gastric cancer (GC) is characterized by a high tumor mutational burden, increased lymphocytic infiltration, and enhanced inflammatory cytokines. GC patients with MSI‐H status have a good response to immune checkpoint blockade management. However, heterogeneity within the subtype and the underlying mechanisms of shaping tumor microenvironments...

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PMID: 35789544
DOI: 10.1002/cam4.4975

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