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Selective usage of ANP32 proteins by influenza B virus polymerase: Implications in determination of host range

12 Oct 2020

Abstract excerpt

The influenza B virus (IBV) causes seasonal influenza and has accounted for an increasing proportion of influenza outbreaks.IBV mainly causes human infections and has not been found to spread in poultry.The replication mechanism and the determinants of interspecies transmission of IBV are largely unknown.In this study, we found that the host ANP32 proteins are required for the function of the IBV polymerase.Human...

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PMID: 33045004
DOI: 10.1371/journal.ppat.1008989

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