Article

Advancing Microbial Comparative Genomics Through Tumor-Normal Inspired Framework

2025-02-05

Abstract excerpt

Comparative genomics has emerged as a pivotal methodology for elucidating genetic variations in microbial studies. However, conventional analytical approaches for diploid and polyploid microorganisms have demonstrated limited efficacy in discriminating new mutations from background heterozygosity. This study presents an innovative microbial comparative genomics framework adapted from tumor-normal sequencing method...

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Literature Corpus work: 793f504b-d303-518e-974b-0e45f9b98208
DOI: 10.1101/2025.02.05.636605

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