Article
Analysis of the Saccharomyces cerevisiae pan-genome reveals a pool of copy number variants distributed in diverse yeast strains from differing industrial environments.
Genome research - 1 May 2012
Dunn Barbara, Richter Chandra, Kvitek Daniel J, Pugh Tom, Sherlock Gavin
Abstract excerpt
Although the budding yeast Saccharomyces cerevisiae is arguably one of the most well-studied organisms on earth, the genome-wide variation within this species--i.e., its "pan-genome"--has been less explored. We created a multispecies microarray platform containing probes covering the genomes of several Saccharomyces species: S. cerevisiae, including regions not found in the standard laboratory S288c strain, as...
Topics
- Chromosome Mapping
- Cluster Analysis
- Comparative Genomic Hybridization
- DNA Copy Number Variations
- DNA Transposable Elements
- Genetic Variation
- Genome, Fungal
- Genome, Mitochondrial
- Hybridization, Genetic
- Plasmids
- Principal Component Analysis
- Recombination, Genetic