Article

Phage-plasmids spread antibiotic resistance genes through infection and lysogenic conversion

2022-06-25

Abstract excerpt

Antibiotic resistance is rapidly spreading by horizontal transfer of resistance genes in mobile genetic elements. While plasmids are key drivers of this process, very few integrative phages encode antibiotic resistance genes. Here, we find that phage-plasmids, elements that are both phages and plasmids, often carry antibiotic resistance genes. We found 60 phage-plasmids with 184 antibiotic resistance genes, includ...

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Literature Corpus work: 793c16b5-d752-5c5f-b854-dbd31a6193b6
DOI: 10.1101/2022.06.24.497495

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