Article

Plasmids link antibiotic resistance genes and phage defense systems in <i>E. coli</i>

2025-07-27

Abstract excerpt

Phage therapy has been proposed as an alternative to antibiotics to treat resistant infections. However, we have a limited understanding of how antibiotic resistance genes (ARGs) associate with bacterial phage defense systems (PDSs). Here, we explore the relationship between ARGs and PDSs in a sample of 2,559 plasmids originating from 1,044 E. coli isolates, representing a snapshot of clinical and non-clinical di...

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Literature Corpus work: 7e27a210-d54d-5152-a9a2-c98a2adefbf1
DOI: 10.1101/2025.07.25.666796

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