Back to search

Article

Immune disease dialogue of chemokine-based cell communications as revealed by single-cell RNA sequencing meta-analysis

2024-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Immune-mediated diseases are characterized by aberrant immune responses, posing significant challenges to global health. In both inflammatory and autoimmune diseases, dysregulated immune reactions mediated by tissue-residing immune and non-immune cells precipitate chronic inflammation and tissue damage that is amplified by peripheral immune cell extravasation into the tissue. Chemokine receptors...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
790ab65a-2a96-5672-85c6-50871a782d38
DOI
10.1101/2024.07.17.603936
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Immune disease dialogue of chemokine-based cell communications as revealed by single-cell RNA sequencing meta-analysisDOI 10.1101/2024.07.17.603936
Unveiling the crucial role of CD8+ T cell and endothelial cell interaction in rheumatoid arthritis through the integrated analysis of spatial transcriptomics and bulk/single-cell RNA-seqSemantic proximity
Characterizing cellular subpopulations critical to treatment response in autoimmune diseasesSemantic proximity
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseasesSemantic proximity
Peripheral Blood Single-Cell Sequencing Uncovers Common and Specific Immune Aberrations in Fibrotic Lung DiseasesSemantic proximity
Single-cell sequencing of PBMC characterizes the transformation of T cell subsets in the inflammatory microenvironment of RA-ILDSemantic proximity
Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritisSemantic proximity
Investigating cellular dynamics and molecular pathways through single-cell RNA sequencing in an imiquimod-induced lupus-like modelSemantic proximity
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation.Semantic proximity
Unraveling immune cell heterogeneity in autoimmune arthritis: insights from single-cell RNA sequencingSemantic proximity
Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid ArthritisSemantic proximity
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.Semantic proximity
Generation of a T cell receptor, cytokine and cell repertoire synovial fluid atlas to define commonalities and dissimilarities between arthritic diseases through systems immunology approachesSemantic proximity
Select a neighboring publication to make it the new centre.