Article

Skeletal muscle reprogramming by breast cancer regardless of treatment history or tumor molecular subtype

2019-10-21

Abstract excerpt

<h4>ABSTRACT</h4> Increased susceptibility to fatigue is a negative predictor of survival commonly experienced by women with breast cancer. Here, we sought to identify molecular changes induced in human skeletal muscle by BC regardless of treatment history or tumor molecular subtype using RNA-sequencing and proteomic analyses. Mitochondrial dysfunction was apparent across all molecular subtypes, with the greatest...

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Literature Corpus work: 7880a802-c49b-5ed5-97a6-39372d7b5a5c
DOI: 10.1101/810952

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