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Article

Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer.

Cancer research communications - 15 May 2024

Wang Ruizhong, Khatpe Aditi S, Kumar Brijesh, Mang Henry Elmer, Batic Katie, Adebayo Adedeji K, Nakshatri Harikrishna

Abstract excerpt

Cancer-induced skeletal muscle defects differ in severity between individuals with the same cancer type. Cancer subtype-specific genomic aberrations are suggested to mediate these differences, but experimental validation studies are very limited. We utilized three different breast cancer patient-derived xenograft (PDX) models to correlate cancer subtype with skeletal muscle defects. PDXs were derived from brain...

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Identifiers

PMID: 38651826
DOI: 10.1158/2767-9764.CRC-24-0045
PMCID: PMC11094532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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