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Article

IL-4 shaping glutamatergic synapse like structures for more mature iPSC derived neuron phenotypes

2023-12-06

Abstract excerpt

The prototypical pleiotropic anti-inflammatory cytokine IL-4 not only acts on immune cells but also has important roles in the nervous system mediating antinociception and neuroregeneration. Therefore, we explored the expression of IL-4, its receptors IL4RA and IL13RA1 and downstream signaling components together with morphological and functional assays as well as transcriptomic profiling in human nociceptors diff...

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Literature Corpus work
78752b65-ed6d-5842-85dd-92f51bd462de
DOI
10.1101/2023.12.05.570057
Open publication

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IL-4 shaping glutamatergic synapse like structures for more mature iPSC derived neuron phenotypesDOI 10.1101/2023.12.05.570057
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