Article

Pericentromeric Transcription of Novel Pathogen-Related Human GPS Genes in Cancers is Regulated by C19MC miRNAs, CEBPB, IFN-γ, and IFN-β

2026-02-04

Abstract excerpt

<title>Abstract</title> <p> Pericentromeric transcription is unique to testis, and oocytes among the normal tissues. However, its regulation in cancer is not well-understood. Here, we discover a novel human, intron-less, coding, pericentromeric GPS gene family in cancer cells, with protein-level homology to microbial proteins from <italic>Plasmodium</italic> , <italic>Staphylococcus, Streptococcus</italic> ,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 785d4de7-06b5-5d75-82d6-6366a865008b
DOI: 10.21203/rs.3.rs-8621807/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pericentromeric Transcription of Novel Pathogen-Related Human GPS Genes in Cancers is Regulated by C19MC miRNAs, CEBPB, IFN-γ, and IFN-βDOI 10.21203/rs.3.rs-8621807/v1Read

Beyond the Genome: Microproteins Unveiling New Dimensions in CancerSemantic proximity Read

PTBP2-Mediated Alternative Splicing of IRF9 Controls Tumor-Associated Monocyte/Macrophage Chemotaxis and Repolarization in Neuroblastoma ProgressionSemantic proximity Read

Structural, molecular, and functional insights into Schlafen proteinsSemantic proximity Read

Multifaceted Roles of Guanylate-Binding Proteins in CancerSemantic proximity Read

Computational prediction of Mycoplasma hominis proteins targeting in nucleus of host cell and their implication in prostate cancer etiologySemantic proximity Read

Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerasesSemantic proximity Read

The CAP Superfamily: Cysteine-Rich Secretory Proteins, Antigen 5, and Pathogenesis-Related 1 Proteins—Roles in Reproduction, Cancer, and Immune DefenseSemantic proximity Read

Identification of Proteins Interacting with Human SP110 During the Process of Viral InfectionsSemantic proximity Read

Pan-cancer Analysis Reveals the Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) Its Significance in Human CancersSemantic proximity Read

Biology of PEST‐Containing Nuclear Protein: A Potential Molecular Target for Cancer ResearchSemantic proximity Read

The Speckled Protein (SP) Family: Immunity's Chromatin Readers.Semantic proximity Read

Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomesSemantic proximity Read