Article

Nanopore Long-Read Transcriptomics Profiling Reveals Gene Expression Signatures of Mouse Tumor Endothelial Cells 2H-11

2021-12-28

Abstract excerpt

<h4>Background: </h4> Tumor endothelial cells (TECs) play an indispensable role in tumor growth and metastasis. Compared with normal endothelial cells (NECs), TECs exhibit unique phenotypic and functional heterogeneity in terms of metabolism, genetics, and transcriptomics. It is not only the key to coordinate tumor angiogenesis, but also an important factor of immune regulation in the tumor microenvironment. In re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 785bc4dd-7b5c-57b9-acdf-567a7e8d0681
DOI: 10.21203/rs.3.rs-1129675/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Nanopore Long-Read Transcriptomics Profiling Reveals Gene Expression Signatures of Mouse Tumor Endothelial Cells 2H-11DOI 10.21203/rs.3.rs-1129675/v1Read

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates.Semantic proximity Read

Single-Cell RNA Sequencing Reveals Heterogeneity and Functional Diversity of Lymphatic Endothelial CellsSemantic proximity Read

Pan-cancer landscape of basement membrane: multi-omics research and single-cell sequencing validation.Semantic proximity Read

Dissecting small cell carcinoma of the esophagus ecosystem by single-cell transcriptomic analysisSemantic proximity Read

Transcriptional Heterogeneity of Tumor-Associated High Endothelial Venules Defines Inflammatory and Stress-Metabolic States with Distinct Prognostic AssociationsSemantic proximity Read

TNMplot.com: a web tool for the comparison of gene expression in normal, tumor and metastatic tissuesSemantic proximity Read

Multi-omics analysis reveals a pericyte-associated gene expression signature for predicting prognosis and therapeutic responses in solid cancersSemantic proximity Read

Integrated Single Cell Atlas of Endothelial Cells of the Human LungSemantic proximity Read

Renal Endothelial Single-Cell Transcriptomics Reveals Spatiotemporal Regulation and Divergent Roles of Differential Gene Transcription and Alternative Splicing in Murine Diabetic NephropathySemantic proximity Read

Transcriptomic Profiles from Normal and Tumor Tissue Samples Reveal Distinct Venule Populations and Novel Tumor Endothelial Cell Markers in Breast CancerSemantic proximity Read

Pan-cancer integrative analyses dissect the remodeling of endothelial cells in human cancersSemantic proximity Read

Uncovering the heterogeneity of pancreatic endothelial cells using integrative and comparative single cell gene expression analysisSemantic proximity Read