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Identification and characterisation of small-molecule inhibitors of Shiga toxin expression in Escherichia coli O157:H7

2019-01-01

Abstract excerpt

Shiga toxin (Stx) producing E. coli (STEC) infections represent an important public health problem given the severity of the disease and sequelae associated to it. Since the use of antibiotics enhances the virulence of STEC, new therapeutic strategies are urgently required. Thus, the main aim of this project is the study of small molecules that are able to block expression of Shiga toxin in Escherichia coli O157:H...

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Literature Corpus work
7843dd15-09ef-58bb-8cb1-a32293ce3b64
DOI
10.5525/gla.thesis.40993
Open publication

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Identification and characterisation of small-molecule inhibitors of Shiga toxin expression in Escherichia coli O157:H7DOI 10.5525/gla.thesis.40993
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