Article

Quinoclamine inhibits Shiga toxin production in enterohemorrhagic <i>Escherichia coli</i>

2023-09-26

Abstract excerpt

<h4>Objectives</h4> Enterohemorrhagic Escherichia coli (EHEC) is responsible for the most severe symptoms of E. coli infections, including hemorrhagic colitis and hemorrhagic uremic syndrome. Shiga toxin 2 (Stx2) plays a significant role as a major virulence factor. The genes encoding Stx2 locate in lambda-like prophage on the EHEC genome. Consequently, Stx2 is expressed when production of the phage is induced...

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Literature Corpus work: 75680d50-32d4-5ada-8db2-97ed345847d5
DOI: 10.1101/2023.09.26.559460

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