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Characterizing RecA-Independent Induction of Shiga toxin2-Encoding Phages by EDTA Treatment

29 Feb 2012

Abstract excerpt

BACKGROUND: The bacteriophage life cycle has an important role in Shiga toxin (Stx) expression. The induction of Shiga toxin-encoding phages (Stx phages) increases toxin production as a result of replication of the phage genome, and phage lysis of the host cell also provides a means of Stx toxin to exit the cell. Previous studies suggested that prophage induction might also occur in the absence of SOS response,...

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PMID: 22393404
DOI: 10.1371/journal.pone.0032393

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