Article

Genomics of chronic cough unravels neurological pathways

2024-07-24

Abstract excerpt

<h4>Background</h4> Chronic cough is a symptom of common lung conditions, occurs as a side effect of ACE inhibitors (ACEis), or may be unexplained. Despite chronic cough representing a substantial health burden, its biological mechanisms remain unclear. We hypothesised shared genetic architecture between chronic dry cough and ACEi-induced cough and aimed to identify causal genes underlying both phenotypes. <h4>Met...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e8e7b066-80ae-51d7-a284-687e4e161886
DOI: 10.1101/2024.07.23.24310853

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genomics of chronic cough unravels neurological pathwaysDOI 10.1101/2024.07.23.24310853Read

Genomics of chronic dry cough unravels neurological pathwaysSemantic proximity Read

Genome-wide association study of ACE inhibitor-induced cough implicates neuropeptides and shows genetic overlap with chronic dry coughSemantic proximity Read

PNPT1 and PCGF3 variants associated with angiotensin-converting enzyme inhibitor-induced cough: a nested case-control genome-wide study.Semantic proximity Read

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough.Semantic proximity Read

Distribution of chronic cough phenotypes in the general population: A cross-sectional analysis of the LEAD cohort in Austria.Semantic proximity Read

FeNO as a Treatable Trait in Chronic Cough: Insights from the PROCOUGH Study.Semantic proximity Read

Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population.Semantic proximity Read

Phenotypes of cough in children: a latent class analysisSemantic proximity Read

Clinical phenotypes of chronic cough categorised by cluster analysis.Semantic proximity Read

Phenotypes of cough in children: A latent class analysis.Semantic proximity Read

Channel synapse mediates neurotransmission of airway protective chemoreflexesSemantic proximity Read

Cluster analysis in 975 patients with current cough identifies a phenotype with several cough triggers, many background disorders, and low quality of lifeSemantic proximity Read