Article

Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

2024-08-28

Abstract excerpt

Breast cancer (BC) is the most common type of cancer among women worldwide and underlies relapse, disease progression and metastasis. Resistance to chemotherapy and programmed cell death (PCD), including apoptosis, strongly affects therapy success and remains a major challenge. Representative and translational models to understand, manipulate and cultivate advanced BC and to model PCD resistance are therefore urge...

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Identifiers and source

Literature Corpus work: 7817d980-70d1-5adf-9b86-c4bb1d4fea86
DOI: 10.1101/2024.08.28.610103

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