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PANoptosis in cancer, the triangle of cell death

1 Dec 2023

Abstract excerpt

BACKGROUND: PANoptosis is a novel form of programmed cell death (PCD) found in 2019 that is regulated by the PANoptosome. PANoptosis combines essential features of pyroptosis, apoptosis, and necroptosis, forming a "death triangle" of cells. While apoptosis, pyroptosis, and necroptosis have been extensively studied for their roles in human inflammatory diseases and many other clinical conditions, historically they...

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PMID: 38069556
DOI: 10.1002/cam4.6803

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