Article

Integrated Evaluation of TRK Expression in Gastric Adenocarcinoma: Correlation with Immunohistochemistry- and In Situ Hybridization–Based Molecular Classification and Diagnostic Challenges

2026-05-11

Abstract excerpt

<title>Abstract</title> <p>Background Identification of neurotrophic tyrosine receptor kinase (NTRK) gene fusions has become clinically important because of the tumor-agnostic effectiveness of TRK inhibitors. In gastric adenocarcinoma (G-ACa), NTRK fusions are known to be exceedingly rare (0–1%), and their clinicopathological associations as well as the performance and reliability of diagnostic approaches remain...

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Literature Corpus work: 7811bbab-d3a2-55c4-83a4-e89b82ba17b5
DOI: 10.21203/rs.3.rs-9258096/v1

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