Article

Store-Operated Calcium Entry Controls Innate and Adaptive Immune Cell Function in Inflammatory Bowel Disease

2021-09-15

Abstract excerpt

<h4>Objective</h4> Inflammatory bowel disease (IBD) is characterized by dysregulated intestinal immune responses and constitutes a major clinical challenge in need of new treatment modalities to improve patient care. Store-operated Ca 2+ entry (SOCE) is the predominant Ca 2+ influx pathway in T cells and other immune cells, regulating many of their functional properties. It is currently unknown whether the pharmac...

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Literature Corpus work: 77feee38-12ed-513e-b6f3-da17082488a8
DOI: 10.1101/2021.09.11.21263401

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