Article

JAM-A functions as a female microglial tumor suppressor in glioblastoma

2019-09-08

Abstract excerpt

Glioblastoma (GBM) remains refractory to treatment. In addition to its cellular and molecular heterogeneity, epidemiological studies indicate the presence of additional complexity associated with biological sex. GBM is more prevalent and aggressive in male compared to female patients, suggesting the existence of sex-specific growth, invasion, and therapeutic resistance mechanisms. While sex-specific molecular mech...

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Literature Corpus work: 77f4a2b6-fa83-5625-851b-f64780397592
DOI: 10.1101/761445

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