Article

miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma

2024-03-12

Abstract excerpt

<h4>Background</h4> Biological sex is an important risk factor for glioblastoma (GBM), with males having a higher incidence and poorer prognosis. The mechanisms for this sex bias are thought to be both tumor intrinsic and tumor extrinsic. MicroRNAs (miRNAs), key post-transcriptional regulators of gene expression, have been previously linked to sex differences in various cell types and diseases, but their role in...

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Literature Corpus work: a9dbff28-c141-5f5d-a64e-dcfa8be0c267
DOI: 10.1101/2024.03.11.584443

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