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Platelets regulate glioblastoma growth and immunity via sex-dependent PAR4 - Estrogen receptor beta signaling

2025-08-08

Abstract excerpt

Sex differences in cancer outcome, including that of glioblastoma (GBM), are shaped by biological, hormonal, and immunological factors and impact disease progression, treatment responses, survival, and tumor microenvironment (TME) interactions. Platelets regulate the immune responses and tumor progression in many cancers, but it is not clear how they contribute to these sex-based differences by affecting the dynam...

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Literature Corpus work
98ab2bea-4ba7-5538-8cf8-9c15858c1bc2
DOI
10.1101/2025.08.06.668464
Open publication

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Platelets regulate glioblastoma growth and immunity via sex-dependent PAR4 - Estrogen receptor beta signalingDOI 10.1101/2025.08.06.668464
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