Article
Sex-specific T cell exhaustion drives differential immune responses in glioblastoma
2022-08-18
Abstract excerpt
Sex differences in glioblastoma (GBM) incidence and outcome are well recognized, and emerging evidence suggests that these extend to genetic/epigenetic and cellular differences, including immune responses. However, the mechanisms driving immunological sex differences are not fully understood. Using GBM models, we demonstrate that T cells play a critical role in driving GBM sex differences. Male mice exhibited acce...
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Identifiers and source
- Literature Corpus work
- f665a1e8-bbd8-5b3f-8500-44cc7b013c4d
- DOI
- 10.1101/2022.08.17.503211