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Article

Cellular mechanisms and effects of interleukin-4 receptor alpha blockade in a novel murine model of conjunctivitis evoked by skin inflammation

2022-05-26

Abstract excerpt

<title>Abstract</title> <p>Ocular surface diseases, including conjunctivitis, are recognized as a common comorbidity in atopic dermatitis (AD) and also occur at an increased frequency in AD patients treated with biologics targeting interleukin-4 receptor alpha (IL-4Ra) or IL-13. However, the inflammatory mechanisms underlying this pathology are unknown. Here, we developed a novel mouse model of skin inflammation-...

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Literature Corpus work
77f19add-2bc6-57ff-a008-4e55a588ef30
DOI
10.21203/rs.3.rs-1669593/v1
Open publication

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Cellular mechanisms and effects of interleukin-4 receptor alpha blockade in a novel murine model of conjunctivitis evoked by skin inflammationDOI 10.21203/rs.3.rs-1669593/v1
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