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Article

Atopic dermatitis-like skin lesions with IgE hyperproduction and pruritus in KFRS4/Kyo rats.

Journal of dermatological science - 1 Nov 2015

Kuramoto Takashi, Yokoe Mayuko, Tanaka Daisuke, Yuri Azusa, Nishitani Ai, Higuchi Yuki, Yoshimi Kazuto, Tanaka Miyuu, Kuwamura Mitsuru, Hiai Hiroshi, Kabashima Kenji, Serikawa Tadao

Abstract excerpt

BACKGROUND: Rats showing spontaneous atopic dermatitis (AD)-like skin lesions were observed in the Kyoto Fancy Rat Stock 4 (KFRS4) strain breeding colony. OBJECTIVE: To establish the KFRS4 rat as a model of AD. METHODS: The clinical symptoms of AD-like skin lesions were assessed by scoring the degree of dermatitis and examining scratching behavior. The transepidermal water loss was measured to evaluate skin...

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Identifiers

PMID: 26454563
DOI: 10.1016/j.jdermsci.2015.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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