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Article

Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IkappaBzeta-/- mice.

Investigative ophthalmology & visual science - 1 Aug 2008

Ueta Mayumi, Hamuro Junji, Ueda Eiichiro, Katoh Norito, Yamamoto Masahiro, Takeda Kiyoshi, Akira Shizuo, Kinoshita Shigeru

Abstract excerpt

PURPOSE: IkappaBzeta(-/-) mice have been reported to be affected by allergic dermatitis. This study was conducted to analyze the pathophysiological role of IkappaBzeta and to address the functional relevance of Th2-mediated immune responses in the development of ocular surface inflammation and dermatitis by IkappaBzeta(-/-) mice. METHODS: BALB/c background IkappaBzeta(-/-) mice were established without individual...

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Identifiers

PMID: 18441309
DOI: 10.1167/iovs.08-1691

Genes

CCL11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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