Article

Detection of hematopoietic stem cell transcriptome in human fetal kidneys and kidney organoids derived from human induced pluripotent stem cells (iPSC)

2021-01-23

Abstract excerpt

<h4>Background</h4> In mammalians, hematopoietic stem cells (HSC) arise in the dorsal aorta from the hemogenic endothelium, followed by their migration to fetal liver and to bone marrow. In zebrafish, kidney is the site of primary hematopoiesis. In humans, the presence of HSC in the fetal or adult kidney has not been established. <h4>Methods</h4> We analyzed the presence of HSC markers in human fetal kidneys by...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 77ee43bf-aaa0-56b6-9951-7f6627f6dc02
DOI: 10.1101/2021.01.22.427745

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Detection of hematopoietic stem cell transcriptome in human fetal kidneys and kidney organoids derived from human induced pluripotent stem cells (iPSC)DOI 10.1101/2021.01.22.427745Read

High throughput single cell RNA-seq of developing mouse kidney and human kidney organoids reveals a roadmap for recreating the kidneySemantic proximity Read

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidneySemantic proximity Read

Single-cell analysis of progenitor cell dynamics and lineage specification of the human fetal kidneySemantic proximity Read

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney developmentSemantic proximity Read

Single-cell analysis reveals congruence between kidney organoids and human fetal kidneySemantic proximity Read

Human fetal kidney organoids model early human nephrogenesis and Notch-driven cell fateSemantic proximity Read

A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem CellsSemantic proximity Read

A Toolbox to Characterize Human Induced Pluripotent Stem Cell–Derived Kidney Cell Types and OrganoidsSemantic proximity Read

A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery.Semantic proximity Read

Cellular and Molecular Mechanisms of Kidney Development: From the Embryo to the Kidney OrganoidSemantic proximity Read

Kidney organoids: Research in developmental biology and emerging applicationsSemantic proximity Read

Fate-mapping within human kidney organoids reveals conserved mammalian nephron progenitor lineage relationshipsSemantic proximity Read