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Cellular and Molecular Mechanisms of Kidney Development: From the Embryo to the Kidney Organoid

24 Mar 2020

Abstract excerpt

Development of the metanephric kidney is strongly dependent on complex signaling pathways and cell-cell communication between at least four major progenitor cell populations (ureteric bud, nephron, stromal and endothelial progenitors) in the nephrogenic zone. In recent years, the improvement of human-PSC-derived kidney organoids has opened new avenues of research on kidney development, physiology, and diseases....

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PMID: 32266264
DOI: 10.3389/fcell.2020.00183

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