Article

Screening cell-cell communication in spatial transcriptomics via collective optimal transport

2022-08-26

Abstract excerpt

Spatial transcriptomic technologies and spatially annotated single cell RNA-sequencing (scRNA-seq) datasets provide unprecedented opportunities to dissect cell-cell communication (CCC). How to incorporate the spatial information and complex biochemical processes in reconstructing CCC remains a major challenge. Here we present COMMOT to infer CCC in spatial transcriptomics, which accounts for the competition among...

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Identifiers and source

Literature Corpus work: 35fa4bec-dd56-5c20-bcba-af9a1fa81764
DOI: 10.1101/2022.08.24.505185

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