Article

Maid gene dysfunction promotes hyperobesity via the reduction of anti-inflammatory macrophages in Mc4r gene-deficient mice

2024-04-30

Abstract excerpt

<title>Abstract</title> <p>The onset and progression mechanisms of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) are being studied. We developed and analyzed a new mouse model of obesity by combining maternal Id-like molecule (Maid) and melanocortin-4 receptor (Mc4r) gene deletions. Eight female mice were analyzed for each genotype: Mc...

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Literature Corpus work: 77bafece-ab4a-5f7e-b06b-5c30f9c89b87
DOI: 10.21203/rs.3.rs-4279233/v1

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