Article

Differences Between Therapeutic Mechanisms of Resmetirom and Semaglutide Against MASH in Western diet-fed MC4R Knockout Mice

2025-05-26

Abstract excerpt

<title>Abstract</title> <p>Metabolic dysfunction-associated steatotic liver disease (MASLD) can progress to metabolic dysfunction-associated steatohepatitis (MASH), which is closely linked to obesity and insulin resistance. Resmetirom, the first approved drug for MASH, and semaglutide, a GLP-1 receptor agonist, have shown therapeutic effects in clinical studies. This study aimed to compare their mechanisms in Wes...

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Literature Corpus work: dd839bc6-c0ef-5ad3-a68c-ea8863945428
DOI: 10.21203/rs.3.rs-6684850/v1

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