Article

Tumor Priming by Ultrasound Mechanogenetics for with SynNotch CAR T Therapy

2024-10-01

Abstract excerpt

Cell-based cancer immunotherapy holds potential as a therapeutic approach, yet its application for solid tumor treatment remains challenging. We created a system where focused ultrasound (FUS) is able to remotely stimulate gene expressions in a specific tissue area through mechanical induction, gated by a chemical inducer to minimize the background noise. This system, known as CaDox, integrates FUS-triggered mecha...

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Literature Corpus work: 77ba2c19-80a7-5b23-ab50-e23c33a883ea
DOI: 10.1101/2024.10.01.615989

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