Article

Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy

2023-09-25

Abstract excerpt

<h4>ABSTRACT</h4> Endometrial decidualization, a prerequisite for successful pregnancies, relies on transcriptional reprogramming driven by progesterone receptor (PR) and bone morphogenetic protein (BMP)-SMAD1/SMAD5 signaling pathways. Despite their critical roles in early pregnancy, how these pathways intersect in reprogramming the endometrium into a receptive state remains unclear. To define how SMAD1 and/or SM...

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Literature Corpus work: 77aa3931-c50a-5722-ae54-2eae188df21f
DOI: 10.1101/2023.09.25.559321

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