Article

Impaired bone morphogenetic protein signaling pathways disrupt decidualization in endometriosis

2023-09-22

Abstract excerpt

<h4>ABSTRACT</h4> It is hypothesized that impaired endometrial decidualization contributes to decreased fertility in individuals with endometriosis. To identify the molecular defects that underpin defective decidualization in endometriosis, we subjected endometrial stromal cells from individuals with or without endometriosis to time course in vitro decidualization with estradiol, progesterone, and 8-bromo-cyclic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e1a8b8a9-d671-56a9-97db-8f60e7295810
DOI: 10.1101/2023.09.21.558268

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Impaired bone morphogenetic protein signaling pathways disrupt decidualization in endometriosisDOI 10.1101/2023.09.21.558268Read

Molecular Basis of Impaired Decidualization in the Eutopic Endometrium of Endometriosis PatientsSemantic proximity Read

Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosisSemantic proximity Read

Endometrial stromal PRMT5 plays a crucial role in decidualization by regulating NF-κB signaling in endometriosisSemantic proximity Read

Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial RegulatorsSemantic proximity Read

New concepts on the etiology of endometriosisSemantic proximity Read

Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis PatientsSemantic proximity Read

BMP4 in Human Endometrial Stromal Cells Can Affect Decidualization by Regulating FOXO1 ExpressionSemantic proximity Read

Transcriptomic responses to hypoxia in endometrial and decidual stromal cellsSemantic proximity Read

CFP1 governs uterine epigenetic landscapes to intervene in progesterone responses for uterine physiology and suppression of endometriosisSemantic proximity Read

Genomic insights into endometriosis, adenomyosis, and uterine fibroids for the clinician.Semantic proximity Read

Steroidogenic Enzyme and Key Decidualization Marker Dysregulation in Endometrial Stromal Cells from Women with Versus Without Endometriosis1Semantic proximity Read

Transcriptomic Changes During the Pre-Receptive to Receptive Transition in Human Endometrium Detected by RNA-SeqSemantic proximity Read