Article
Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.
Nucleic acids research - 1 Feb 2013
Yamaji Daisuke, Kang Keunsoo, Robinson Gertraud W, Hennighausen Lothar
Abstract excerpt
The transcription factors Signal Transducer and Activator of Transcription (STAT) 5A/B mediate prolactin-induced mammary development during pregnancy. However, it is not clear how the different processes, expansion and maturation of alveolar precursor cells and the differential induction of milk protein genes are regulated on a molecular level. We have used mouse genetics and genome-wide analyses to determine how...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
