Article

Genome-Wide Association Study of Creatinine Clearance Identifies New Loci for Kidney Function

2026-03-05

Abstract excerpt

<h4>Introduction</h4> Genome-wide association studies (GWAS) for kidney function have mainly focused on creatinine-based glomerular filtration rate (eGFR crea ), which is affected by variation in muscle mass. Moreover, the genetic basis of the sexual dimorphism of chronic kidney disease is underexplored. <h4>Methods</h4> We performed a GWA meta-analysis for creatinine clearance (CrCl), a muscle mass-independen...

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Literature Corpus work: 7763a13d-5080-5dee-85ab-66205e286d23
DOI: 10.64898/2026.03.04.26347652

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