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Article

Genome-wide association study of creatinine clearance identifies new loci for kidney function.

Kidney international - 1 Sept 2026

Argoty-Pantoja Anna D, van der Most Peter J, Kamali Zoha, Ganji-Arjenaki Mahboube, van der Vaart Amarens, Vaez Ahmad, Bakker Stephan J L, Snieder Harold, de Borst Martin H

Abstract excerpt

INTRODUCTION: Genome-wide association studies (GWAS) for kidney function have mainly focused on creatinine-based glomerular filtration rate (eGFRcrea), which is affected by variation in muscle mass. Moreover, the genetic basis of the sexual dimorphism of chronic kidney disease is underexplored. METHODS: We performed a GWAS meta-analysis for creatinine clearance (CrCl), a muscle mass-independent measure of kidney...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, IGF Type 1

Share to Renal Insufficiency, Chronic

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Source

Identifiers

PMID: 42302930
DOI: 10.1016/j.kint.2026.05.012

Genes

AGPAT4
GPC6
IGF1R
IGF2R
RP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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