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The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition

2021-07-15

Abstract excerpt

<h4>ABSTRACT</h4> The minor allele (A) of the rs373863828 variant (p.Arg457Gln) in CREBRF is restricted to indigenous peoples of the Pacific islands (including New Zealand Māori and peoples of Polynesia), with a frequency up to 25% in these populations. This allele associates with a large increase in body mass index (BMI) but with significantly lower risk of type-2 diabetes (T2D). It is unclear whether the increas...

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Literature Corpus work
7758696a-ac48-5151-af44-405d8b32c96a
DOI
10.1101/2021.07.13.21260462
Open publication

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The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body compositionDOI 10.1101/2021.07.13.21260462
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