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Article

The Pacific-specific CREBRF rs373863828 allele protects against gestational diabetes mellitus in Māori and Pacific women with obesity.

Diabetologia - 1 Oct 2020

Krishnan Mohanraj, Murphy Rinki, Okesene-Gafa Karaponi A M, Ji Maria, Thompson John M D, Taylor Rennae S, Merriman Tony R, McCowan Lesley M E, McKinlay Christopher J D

Abstract excerpt

AIMS/HYPOTHESIS: The CREBRF rs373863828 minor (A) allele is associated with increased BMI but reduced prevalence of type 2 diabetes in Māori and Pacific people. Given the shared aetiology of type 2 diabetes and gestational diabetes mellitus (GDM), we tested for an association between the CREBRF rs373863828 variant and GDM. METHODS: We conducted a prospective cohort study of Māori and Pacific women nested within a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32654027
DOI: 10.1007/s00125-020-05202-8

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