Article

Improving leukemic CD34 <sup>+</sup> /CD38 <sup>−</sup> blasts characterization with single-cell transcriptome sequencing

2017-05-31

Abstract excerpt

<h4>SUMMARY / ABSTRACT</h4> Acute myeloid leukemia (AML) is a particularly aggressive blood cancer that is difficult to treat because of the incomplete eradication of rare blast cells that possess self-renewal and leukemia-initiating properties. To characterize resistant blasts, we analyzed for the first time the transcriptomes of individual CD3 4+ /CD38 − blasts by single-cell mRNA sequencing of 359 CD33 + /C...

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Literature Corpus work: 771975ce-c2f2-5a7a-bfc6-7a86f7d9f18b
DOI: 10.1101/141754

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